Eric L. Denovellis

Computational research scientist at UCSF — building scalable, interpretable tools to decode, categorize, and visualize how the brain represents information.

About me

I work in Dr. Loren Frank’s lab developing methods for decoding neural representations – particularly in the hippocampus. My methodological focus is on marked point process switching state space models for characterizing replay dynamics, work I began during my postdoc with Dr. Uri T. Eden. I work closely with experimental collaborators to ensure these methods are usable on large-scale data, and I build open-source infrastructure to make advanced computational techniques accessible to the broader neuroscience community.

Previously, I completed my Ph.D. in computational neuroscience at Boston University with Drs. Daniel H. Bullock and Earl K. Miller. There I developed computational tools and models to understand how prefrontal cortex supports the underlying neural computations necessary to switch between contexts. Specifically:

  • I showed how synchronous network oscillations in the prefrontal cortex provide a mechanism to flexibly coordinate context representations between groups of neurons during task switching.

  • I used generalized additive models to show that anterior cingulate neurons can represent context, but do not play a significant role in switching between contexts.

  • Finally, I developed a set of web-enabled interactive visualization tools designed to provide a multi-dimensional integrated view of electrophysiological datasets (See RasterVis and SpectraVis).

Education

CV

Here is my CV.

Collaborators